Available equipement

I) Chromatography service

UHPLC-MS/MS – Thermo Scientific U3000 + Endura (triple quadrupole)

Separation and analysis of compounds by UHPLC with DAD and triple quadrupole MS detection

  • Qualitative and quantitative analyses
  • TLC-MS of synthetic compounds and plant extracts

Equipped with:

 

  • Column oven
  • Column selector
  • DAD detector
  • ESI and APCI sources
  • TLC-MS interface

 

Software : Thermo Excalibur

 

UHPLC-MS – Thermo Scientific U3000 + MSQ (simple quadrupole)

Separation and analysis of compounds by UHPLC with DAD and simple quadrupole MS detection

  • LC-MS of synthetic compounds (reaction monitoring)

Equipped with:

 

  • Column oven
  • DAD detector
  • ESI and APCI sources

 

Software : Thermo Excalibur

 

 

Hybride UHPLC-SFC UV/ELSD – Shimadzu
Analysis and purification of (a)chirals compounds by liquid and/or supercritical chromatography with DAD and ELSD detection

Equipped with:

 

  • Column oven
  • Columns selector
  • DAD detector
  • ESI and APCI sources

 

Software : LabSolutions

 

Equipment acquired through the APR-IA Centre Val de Loire and the FEDER: TECH SAB project

 

HPLC-UV/ELSD - Agilent 1100

Separation and analysis of compounds by HPLC with DAD and ELSD detection

  • Purity measurement
  • Monitoring of synthetic compounds

Equipped with:

 

  • Column oven
  • DAD detector

 

Software : Agilent ChemStation

 

HPLC preparative – Interchim PuriFlash 4250

Purification and collect of compounds by preparative liquid chromatography with UV and ELSD detection

Equipped with:

 

  • DAD Detector
  • ELSD Detector
  • Until 250 mL/min and 250 bar

 

Software : Intersoft X

 

HPTLC – CAMAG

Separation and analysis of compounds by HPTLC with UV-Vis detection

  • Deposition, elution and revelation of samples (plant extracts)
  • MS identification available thanks to TLC-MS interface (triple quadrupole or MALDI-TOF)

Equipped with:

  • ATS 4 (Automatic TLC Sampler)
  • ADC 2 (Automatic Developing Chamber)
  • Derivatizer
  • TLC Visualizer 2
  • TLC Scanner 3
  • TLC-MS Interface 2

 

Software : visionCATS

 

Equipment acquired through the APR-IA Centre Val de Loire and the FEDER: TECH SAB project

 

GC-FID – Shimadzu 2025

Separation and analysis of volatile compounds by GC-FID (Flame Ionisation Detector)

Equipped with:

  • FID detector
  • Gas generator (H2)

 

Software : Shimadzu LabSolutions

II) Spectroscopy Service

 

UV-Vis Spectrometer – Shimadzu UV-1800

Determination of the absorption λ max, identification and quantification of compounds by UV (200-400 nm) - Visible (400-900nm) spectroscopy
  • UV-Visible : 200-­900 nm

 

Software : UVProbe

 

Spectrofluorimeter – Horiba FluoroMax+

Sample fluorescence measurement, assay and determination of quantum yield
  • Fluorescence : 185-900 nm

 

Software : FluorEssence

 

IRTF Spectrometer – Thermo Scientific Nicolet iS10

Functional identification of compounds by infrared measurement (4000-400 cm-1)
  • ATR diamant ou transmission

 

Software : Omnic

 

Polarimeter – Jasco P2000 Jasco

Determination of the rotatory power αD by polarimetry
  • Na Lamp
  • Filters: 589, 546, 365 nm

 

Manual control
 

III) Interactions studies

MicroScale Thermophoresis – NanoTemper Monolith NT.115 Pico

Study of molecular interactions by MST
  • 16 channels

 

Software : MO.Control/MO.Affinity