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The different topics developed at the Institute of Organic and Analytical Chemistry (ICOA) are directed towards the design, synthesis and analysis of small molecules likely to have biological activities.

The institute is a Mixed Research Unit (UMR 7311) of the University of Orleans and the French National Center for Scientific Research (CNRS).

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Latest productions

Our latest 3 publications

Ejjoummany, A. ; Elie, J. ; El Akkaoui, A. ; Akssira, M. ; Routier, S. ; Buron, F.
Access and modulation of substituted pyrrolo[3,4-c]pyrazole-4,6-(2H,5H)-diones
Molecules 2023, 28, 5811.

Chambaud, M. ; Colas, C. ; Destandau, E.
Water-based microwave-assisted extraction of pigments from madder optimized by a Box–Behnken design
Separations 2023, 10, 433.

West, C. ; Lesellier, E.
Chapter 3 - Selection of SFC stationary and mobile phases
Practical application of supercritical fluid chromatography for pharmaceutical research and development, Separation Science and Technology vol. 14, edited by Michael Hicks & Paul Ferguson 2023, 14, 49-71.

Our latest 2 patents

  1. Morisset-Lopez, S. ; Suzenet, F. ; Guillaumet, G. ; Deau, E. ; Robin, E. ; El Khamlichi, C. ; Reverchon-Assadi, F. ; Hervouet-Coste, N. ; Madouri, F. ; Hiebel, M.-A.
    Applications of biased ligands of the serotonin 5-HT7 receptor for the treatment of pain, multiple sclerosis and the control of thermoregulation
    2. Patent N° Kind Date Application N° Date
    WO2022195102 A1 22 sept. 2022 WO2022-EP57227 18 mars 2022

        Priority Application :
                      EP2021-315045 19 mars 2021
        ref. chem. Abstract : 180:185169

  2. Routier, S. ; Plé, K. ; Gay, M. ; Ben Jamaa, A. ; Chesné, C. ; Li, R. ; Martin, S. ; Daligaux, P.
    Cholic acid Fluorescent probes for in vivo/vitro identification and quantification of hepatic transporters
    3. Patent N° Kind Date Application N° Date
    US20220308043 A1 29 sep. 2022 US2022-17696315 16 mars 2022

        Priority Application :
                      US2021-63161595 16 mars 2021
        ref. chem. Abstract : 2022:2497259