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The different topics developed at the Institute of Organic and Analytical Chemistry (ICOA) are directed towards the design, synthesis and analysis of small molecules likely to have biological activities.

The institute is a Mixed Research Unit (UMR 7311) of the University of Orleans and the French National Center for Scientific Research (CNRS).

ICOA is also a member of:

and is a corresponding lab of French Alternative Energies and Atomic Energy Commission (CEA) LRC M09.

Highlights

Congratulations to Doina SIRBU (Heterocycles, Nucleosides and Imaging Agents research team) for the best poster award at the Young Researchers' Days of the Therapeutic Chemistry Society.
Congratulations to Abdennour BRAKA (Structural Bioinformatics and Computational Chemistry Research Team) for the award of the best communication at the Young Researchers' Days of the Center-Ouest Regional Section of the Société Chimique de France.
Congratulations to Matthieu PLACE (Heterocycles, Nucleosides and Imaging Agents research team) for the award of the best communication award during the Young Researchers' Days of the Center-Ouest Regional Section of the Société Chimique de France.

Latest publications

Giacoppo, S. ; Rajan, T. S. ; De Nicola, G. R. ; Iori, R. ; Rollin, P. ; Bramanti, P. ; Mazzon, E.
The isothiocyanate isolated from Moringa oleifera shows potent anti-inflammatory activity in the treatment of murine subacute Parkinson's disease
Rejuvenation Research 2017, 20, 50-63.

Bosc, N. ; Wroblowski, B. ; Meyer, C. ; Bonnet, P.
Prediction of protein kinase-ligand interactions through 2.5D kinochemometrics
J. Chem. Inf. Model. 2017, 57, 93-101.

Riffault-Valois, L. ; Blanchot, L. ; Colas, C. ; Destandau, E. ; Pasquier, L. ; André, P. ; Elfakir, C.
Molecular fingerprint comparison of closely related rose varieties based on UHPLC-HRMS analysis and chemometrics
Phytochem. Anal. 2017, 28, 42-49.