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The different topics developed at the Institute of Organic and Analytical Chemistry (ICOA) are directed towards the design, synthesis and analysis of small molecules likely to have biological activities.

The institute is a Mixed Research Unit (UMR 7311) of the University of Orleans and the French National Center for Scientific Research (CNRS).

ICOA is also a member of:

and is a corresponding lab of French Alternative Energies and Atomic Energy Commission (CEA) LRC M09.

Highlights

Congratulations to Doina SIRBU (Heterocycles, Nucleosides and Imaging Agents research team) for the best poster award at the Young Researchers' Days of the Therapeutic Chemistry Society.
Congratulations to Abdennour BRAKA (Structural Bioinformatics and Computational Chemistry Research Team) for the award of the best communication at the Young Researchers' Days of the Center-Ouest Regional Section of the Société Chimique de France.
Congratulations to Matthieu PLACE (Heterocycles, Nucleosides and Imaging Agents research team) for the award of the best communication award during the Young Researchers' Days of the Center-Ouest Regional Section of the Société Chimique de France.

Latest publications

Fayad, S. ; Nehmé, R. ; Tannoury, M. ; Lesellier, E. ; Pichon, C. ; Morin, Ph.
Macroalga Padina pavonica water extracts obtained by pressurized liquid extraction and microwave-assisted extraction inhibit hyaluronidase activity as shown by capillary electrophoresis
J. Chromatogr. A 2017, 1497, 19-27.

Duval, J. ; Colas, C. ; Pecher, V. ; Poujol, M. ; Tranchant, J. F. ; Lesellier, E.
Hyphenation of ultra high performance supercritical fluid chromatography with atmospheric pressure chemical ionisation high resolution mass spectrometry: Part 1. Study of the coupling parameters for the analysis of natural non-polar compounds
J. Chromatogr. A 2017, 1509, 132-140.

Fayad, S. ; Nehmé, R. ; Langmajerova, M. ; Ayela, B. ; Colas, C. ; Maunit, B. ; Jacquinet, J. C. ; Vibert, A. ; Lopin-Bon, C. ; Zdenek, G. ; Morin, Ph.
Hyaluronidase reaction kinetics evaluated by capillary electrophoresis with UV and high-resolution mass spectrometry (HRMS) detection
Anal. Chim. Acta 2017, 951, 140-150.