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The different topics developed at the Institute of Organic and Analytical Chemistry (ICOA) are directed towards the design, synthesis and analysis of small molecules likely to have biological activities.

The institute is a Mixed Research Unit (UMR 7311) of the University of Orleans and the French National Center for Scientific Research (CNRS).

ICOA is also a member of:

and is a corresponding lab of French Alternative Energies and Atomic Energy Commission (CEA) LRC M09.

Highlights

Congratulations to Celia SAPPEI (Research team Heterocycles, nucleosides and Imaging Agents) for obtaining Biotechnocentre award for best communication entitled "Synthesis & analysis of regiofunctionalized b-cyclodextrin derivatives by new pyridine carboxylate ligands towards MRI application".
Congratulations to Syntia Fayad (Analytical Team) to obtain the price CJSM 2016 the best scientific presentation entitled "Capillary electrophoresis coupled to high resolution mass spectrometry for the assessment of enzyme kinetics : Application to hyaluronidase".
Congratulations to Cedric Peyrot, from ICOA in close collaboration with the l'ENS-Rennes and GLYcoDiag, received the Award for the best poster presentation for his research on the chemo-enzymatic synthesis of glycolipids. Obtained via biocatalysis, these new bioactive hydrogels are tested as texturing agents for cosmetic applications.

Latest publications

Bosc, N. ; Meyer, C. ; Bonnet, P.
The use of novel selectivity metrics in kinase research
BMC Bioinformatics 2017, 18, 17.

Montaut, S. ; De Nicola, G. R. ; Agnaniet, H. ; Issembe, Y. ; Rollin, P. ; Menut, C.
Probing for the presence of glucosinolates in three Drypetes spp. (Drypetes euryodes (Hiern) Hutch., Drypetes gossweileri S. Moore, Drypetes laciniata Hutch.) and two Rinorea spp. (Rinorea subintegrifolia O. Ktze and Rinorea woermanniana (Buttner) Engl.) from Gabon
Nat. Prod. Res. 2017, 31, 308-313.

Montaut, S. ; Blažević, I. ; Ruščić, M. ; Rollin, P.
LC-MS profiling of glucosinolates in the seeds of Brassica elongata Ehrh., and of the two stenoendemic B. botteri Vis and B. cazzae Ginzb. & Teyber
Nat. Prod. Res. 2017, 31, 58-62.