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The different topics developed at the Institute of Organic and Analytical Chemistry (ICOA) are directed towards the design, synthesis and analysis of small molecules likely to have biological activities.

The institute is a Mixed Research Unit (UMR 7311) of the University of Orleans and the French National Center for Scientific Research (CNRS).

ICOA is also a member of:

and is a corresponding lab of French Alternative Energies and Atomic Energy Commission (CEA) LRC M09.

Highlights

Congratulations to Doina SIRBU (Heterocycles, Nucleosides and Imaging Agents research team) for the best poster award at the Young Researchers' Days of the Therapeutic Chemistry Society.
Congratulations to Abdennour BRAKA (Structural Bioinformatics and Computational Chemistry Research Team) for the award of the best communication at the Young Researchers' Days of the Center-Ouest Regional Section of the Société Chimique de France.
Congratulations to Matthieu PLACE (Heterocycles, Nucleosides and Imaging Agents research team) for the award of the best communication award during the Young Researchers' Days of the Center-Ouest Regional Section of the Société Chimique de France.

Latest publications

Thiebault, T. ; Chassiot, L. ; Fougère, L. ; Destandau, E. ; Simonneau, A. ; Van Beek, P. ; Souhaut, M. ; Chapron, E.
Record of pharmaceutical products in river sediments: A powerful tool to assess the environmental impact of urban management?
Anthropocene 2017, 18, 47-56.

West, C. ; Konjaria, M. L. ; Shashviashvili, N. ; Lemasson, E. ; Bonnet, P. ; Kakava, R. ; Volonterio, A. ; Chankvetadze, B.
Enantioseparation of novel chiral sulfoxides on chlorinated polysaccharide stationary phases in supercritical fluid chromatography
J. Chromatogr. A 2017, 1499, 174-182.

Foucault-Fruchard, L. ; Doméné, A. ; Page, G. ; Windsor, M. ; Emond, P. ; Rodrigues, N. ; Dolle, F. ; Damont, A. ; Buron, F. ; Routier, S. ; Chalon, S. ; Antier, D.
Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in-vivo excitotoxic adult rat model
Neuroscience 2017, 356, 52-63.