Publications des 5 dernières années

Vous trouverez ici la liste des publications de l'équipe sur les 5 dernières années, pour avoir l'ensemble des données vous pouvez consulter la page des productions.

Revue à comité de lecture (rang A)

  1. Vasincu, I. M. ; Apotrosoasei, M. ; Constantin, S. ; Butnaru, M. ; Verestiuc, L. ; Lupușoru, C.-E. ; Buron, F. ; Routier, S. ; Lupașcu, D. ; Taușer, R.-G. ; Profire, L.
    New ibuprofen derivatives with thiazolidine-4-one scaffold with improved pharmaco-toxicological profile
    BMC Pharmacol. Toxicol. 2021, 22, 10.
    Impact Factor: 1.771

  2. Vetel, S. ; Foucault-Fruchard, L. ; Tronel, C. ; Buron, F. ; Vergote, J. ; Bodard S. ; Routier, S. ; Sérrière, S. ; Chalon, S.
    Neuroprotective and anti-inflammatory effects of a therapy combining agonists of nicotinic α7 and σ1 receptors in a rat model of Parkinson’s disease
    Neural Regeneration Research 2021, 16, 1099-1104.
    Impact Factor: 3.171

  3. Constantin, S. M. ; Lupascu, F. G. ; Apotrosoasei, M. ; Fosca, A. V. ; Vasincu, I. M. ; Confederat, L. G. ; Dimitriu, G. ; Lupușoru, C.-E. ; Routier, S. ; Buron, F. ; Profire, L.
    Antidiabetic effects and safety profile of chitosan delivery systems loaded with new xanthine-thiazolidine-4-one derivatives: in vivo studies
    Journal of Drug Delivery Science and Technology 2020, 60, 102091.
    Impact Factor: 2.734

  4. Elie, J. ; Feizbakhsh, O. ; Desban, N. ; Josselin, B. ; Baratte, B. ; Bescond, A. ; Duez, J. ; Fant, X. ; Bach, S. ; Marie, D. ; Place, M. ; Ben Salah, S. ; Chartier, A. ; Berteina-Raboin, S. ; Chaikuad, A. ; Knapp, S. ; Carles, F. ; Bonnet, P. ; Buron, F. ; Routier, S. ; Ruchaud, S.
    Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation
    J. Enzym. Inhib. Med. Chem. 2020, 35, 1840–1853.
    Impact Factor: 4.673

  5. Focsa, A. ; Iacob, A. ; Vasincu, I. ; Constantin, S. ; Andriescu, L. ; Sava, A. ; Buron, F. ; Routier, S. ; Apotrosoasei, M. ; Profire, L.
    Optimization of the synthesis of diclofenac derivatives with hydrazone structure and in vitro evaluation of the anti-inflammatory potential
    Revista de Chimie (Bucharest) 2020, 71, 305-314.
    Impact Factor: 1.755

  6. Focsa, A. ; Iacob, A. ; Vasincu, I. ; Constantin, S. ; Andriescu, L. ; Sava, A. ; Buron, F. ; Routier, S. ; Profire, L.
    The antioxidant potential evaluation of diclofenac derivatives with hydrazones structure
    Farmacia 2020, 68, 329-334.
    Impact Factor: 1.607

  7. Soklou, K. E. ; Marzag, H. ; Bouillon, J.-P. ; Marchivie, M. ; Routier, S. ; Plé, K.
    Gold(I)-catalyzed intramolecular hydroamination and hydroalkoxylation of alkynes: access to original heterospirocycles
    Org. Lett. 2020, 22, 5973–5977.
    Impact Factor: 6.091

  8. Vetel, S. ; Vercouillie, J. ; Buron, F. ; Vergote, J. ; Tauber, C. ; Busson, J. ; Chicheri, G. ; Routier, S. ; Sérrière, S. ; Chalon, S.
    Longitudinal PET imaging of α7 nicotinic acetylcholine receptors with [18F]ASEM in a Rat model of Parkinson’s disease
    Molecular Imaging and Biology 2020, 22, 348-357.
    Impact Factor: 2.925

  9. Constantin, S. M. ; Buron, F. ; Routier, S. ; Vasincu, I. M. ; Apotrosoasei, M. ; Lupaşcu, F. ; Confederat, L. ; Tuchilus, C. ; Constantin, M. T. ; Sava, A. ; Profire, L.
    Formulation and characterization of new polymeric systems based on chitosan and xanthine derivatives with thiazolidin-4-one scaffold
    Materials 2019, 12, 558.
    Impact Factor: 3.057

  10. Elie, J. ; Vercouillie, J. ; Arlicot, N. ; Lemaire, L. ; Bidault, R. ; Bodard S. ; Hosselet, C. ; Deloye, J.-B. ; Chalon, S. ; Emond, P. ; Guilloteau, D. ; Buron, F. ; Routier, S.
    Design of selective COX-2 inhibitors in the (aza)indazole series. Chemistry, in vitro studies, radiochemistry and evaluations in rats of a [18F] PET tracer
    J. Enzym. Inhib. Med. Chem. 2019, 34, 1-7.
    Impact Factor: 4.673

  11. Ouach, A. ; Vercouillie, J. ; Bertrand, E. ; Rodrigues, N. ; Pin, F. ; Serriere, S. ; Boiaryna, L. ; Chartier, A. ; Percina, N. ; Tangpong, P. ; Gulhan, Z. ; Mothes C. ; Deloye, J.-B. ; Guilloteau, D. ; Page, G. ; Suzenet, F. ; Buron, F. ; Chalon, S. ; Routier, S.
    Bis(het)aryl-1,2,3-triazole quinuclidines as α7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [18F]-radiolabeling and PET study in rats
    Eur. J. Med. Chem. 2019, 179, 449-469.
    Impact Factor: 5.572

  12. Oukoloff, K. ; Coquelle, N. ; Bartolini, M. ; Naldi, M. ; Le Guével, R. ; Bach, S. ; Josselin, B. ; Ruchaud, S. ; Catto, M. ; Pisani, L. ; Denora, N. ; Iacobazzi, R. M. ; Silman, I. ; Sussman, J. L. ; Buron, F. ; Colletier, J.-P. ; Jean, L. ; Routier, S. ; Renard, P.-Y.
    Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3
    Eur. J. Med. Chem. 2019, 168, 58-77.
    Impact Factor: 5.572

  13. Belaroussi, R. ; Ejjoummany, A. ; El Hakmaoui, A. ; Akssira, M. ; Guillaumet, G. ; Routier, S.
    Three successive and regiocontroled palladium cross-coupling reactions to easily synthesize novel series of 2,4,6-tris(het)aryl pyrido[1′,2′:1,5]pyrazolo[3,4-d]pyrimidines
    RSC Advances 2018, 8, 732-741.
    Impact Factor: 3.049

  14. Ejjoummany, A. ; Belaroussi, R. ; El Hakmaoui, A. ; Akssira, M. ; Guillaumet, G. ; Buron, F. ; Routier, S.
    Regioselective Synthesis of New 2,4-(Het)aryl-3H-pyrido[1′,2′:1,5]pyrazolo[4,3-d]pyrimidines Involving Palladium-Catalyzed Cross-Coupling Reactions
    Molecules 2018, 23, 2740.
    Impact Factor: 3.06

  15. Iacob, A.-T. ; Drăgan, M. ; Ghețu, N. ; Pieptu, D. ; Vasile, C. ; Buron, F. ; Routier, S. ; Giusca, S. E. ; Caruntu, I.-D. ; Profire, L.
    Preparation, characterization and wound healing effects of new membranes based on chitosan, hyaluronic acid and arginine derivatives
    Polymers 2018, 10, 607.
    Impact Factor: 3.164

  16. Laskaris, P. ; Vicentefranqueira, R. ; Helynck, O. ; Jouvion, G. ; Calera, J. A. ; du Merle, L. ; Suzenet, F. ; Buron, F. ; de Sousa, R. A. ; Mansuy, D. ; Cavaillon, J. M. ; Latgé, J. P. ; Munier-Lehmann, H. ; Ibrahim-Granet, O.
    A novel polyaminocarboxylate compound to treat murine pulmonary aspergillosis by interfering with zinc metabolism
    Antimicrob. Agents Chemother. 2018, 62, .
    Impact Factor: 4.255

  17. Laugeray, A. ; Oummadi, A. ; Jourdain, C. ; Feat, J. ; Meyer-Dilhet, G. ; Menuet, A. ; Plé, K. ; Gay, M. ; Routier, S. ; Mortaud, S. ; Guillemin, G. J.
    Perinatal exposure to the cyanotoxin β-N-Methylamino-L-alanine (BMAA) results in long-lasting behavioral changes in offspring-potential involvement of DNA damage and oxidative stress
    Neurotox. Res. 2018, 33, 87-112.
    Impact Factor: 3.311

  18. Burban, A. ; Sharanek, A. ; Hue, R. ; Gay, M. ; Routier, S. ; Guillouzo, A. ; Guguen-Guillouzo, C.
    Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
    Sci. Rep. 2017, 7, 1815.
    Impact Factor: 4.122

  19. Constantin, S. ; Lupascu, F. G. ; Apotrosoasei, M. ; Vasincu, I. M. ; Lupascu, D. ; Buron, F. ; Routier, S. ; Profire, L.
    Synthesis and biological evaluation of the new 1,3-dimethylxanthine derivatives with thiazolidine-4-one scaffold
    Chemistry Central Journal 2017, 11:12, .
    Impact Factor: 2.284

  20. D'Attoma, J. ; Camara, T. ; Brun, P. L. ; Robin, Y. ; Bostyn, S. ; Buron, F. ; Routier, S.
    Efficient transposition of the Sandmeyer reaction from batch to continuous process
    Org. Process Res. Dev. 2017, 21, 44-51.
    Impact Factor: 3.584

  21. Desplat, V. ; Vincenzi, M. ; Lucas, R. ; Moreau, S. ; Savrimoutou, S. ; Rubio, S. ; Pinaud, N. ; Bigat, D. ; Enriquez, E. ; Marchivie, M. ; Routier, S. ; Sonnet, P. ; Rossi, F. ; Ronga, L. ; Guillon, J.
    Synthesis and antiproliferative effect of Ethyl 4-[4-(4-substituted piperidin-1-yl)]benzylpyrrolo[1,2-a]quinoxalinecarboxylate derivatives on Human Leukemia Cells
    ChemMedChem 2017, 12, 940-953.
    Impact Factor: 3.009

  22. Foucault-Fruchard, L. ; Doméné, A. ; Page, G. ; Windsor, M. ; Emond, P. ; Rodrigues, N. ; Dolle, F. ; Damont, A. ; Buron, F. ; Routier, S. ; Chalon, S. ; Antier, D.
    Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in-vivo excitotoxic adult rat model
    Neuroscience 2017, 356, 52-63.
    Impact Factor: 3.382

  23. Ledru, H. ; D'Attoma, J. ; Bostyn, S. ; Routier, S. ; Buron, F. ; Lopin-Bon, C.
    Screening of activation tools to design sulfated saccharides
    ChemistrySelect 2017, 2, 9637-9641.
    Impact Factor: 1.505

  24. Nicolas, C. ; Cocaud, C. ; Maujoin, A. ; Zheng, R. B. ; Lowary, T. L. ; Rodrigues, N. ; Percina, N. ; Chartier, A. ; Buron, F. ; Routier, S. ; Martin, O. R.
    Triazole-linked iminosugars and aromatic systems as simplified UDP-Galf mimics: synthesis and preliminary evaluation as Galf-transferase inhibitors
    Eur. J. Org. Chem. 2017, 6192–6201.
    Impact Factor: 2.882

  25. Place, M. ; Copin, C. ; Apotrosoasei, M. ; Constantin, S. ; Vasincu, I. M. ; Profire, L. ; Buron, F. ; Routier, S.
    Synthesis of [1,3,4]thiadiazolo[3',2':1,2]imidazo[4,5-c]quinolines including Pictet-Spengler reaction and exploration of their C-2 reactivity through SNAr
    J. Org. Chem. 2017, 82, 13700-13707.
    Impact Factor: 4.805

  26. Belaroussi, R. ; El Hakmaoui, A. ; Akssira, M. ; Guillaumet, G. ; Routier, S.
    Regioselective Synthesis of 2,4-Substituted Pyrido[1′,2′:1,5]pyrazolo[3,4-d]pyrimidines through Sequential Pd-Catalyzed Arylation and SNAr Reactions
    Eur. J. Org. Chem. 2016, 3550-3558.
    Impact Factor: 2.834

  27. Champiré, A. ; Vala, C. ; Laabid, A. ; Benharref, A. ; Marchivie, M. ; Plé, K. ; Routier, S.
    Controlled Dimroth rearrangement in the Suzuki-Miyaura cross coupling of triazolopyridopyrimidines
    J. Org. Chem. 2016, 81, 12506-12513.
    Impact Factor: 4.849

  28. Constantin, S. ; Buron, F. ; Routier, S. ; Confederat, L. ; Teodora Pânzariu, A. ; Miron, A. ; Profire, L.
    Studies on xanthine derivatives (ii). Synthesis and antioxidant effects of some hydrazones with xanthine structure
    Farmacia 2016, 64, 565-571.
    Impact Factor: 1.162

  29. Copin, C. ; Henry, N. ; Buron, F. ; Routier, S.
    Palladium-catalyzed direct arylation of 2,6-disubstituted imidazo[2,1-b][1,3,4]thiadiazoles
    Synlett 2016, 27, 1091-1095.
    Impact Factor: 2.419

  30. Copin, C. ; Buron, F. ; Routier, S.
    Palladium-catalyzed amination of C-5 bromoimidazo[2,1-b][1,3,4]thiadiazoles
    Eur. J. Org. Chem. 2016, 1958-1962.
    Impact Factor: 2.834

  31. D'Attoma, J. ; Cozien, G. ; Brun, P. L. ; Robin, Y. ; Bostyn, S. ; Buron, F. ; Routier, S.
    Fast functionalization of (7-aza)indoles using continuous flow processes
    ChemistrySelect 2016, 1, 338-342.
    Impact Factor: ND

  32. Desplat, V. ; Vincenzi, M. ; Lucas, R. ; Moreau, S. ; Savrimoutou, S. ; Pinaud, N. ; Lesbordes, J. ; Peyrilles, E. ; Marchivie, M. ; Routier, S. ; Sonnet, P. ; Rossi, F. ; Ronga, L. ; Guillon, J.
    Synthesis and evaluation of the cytotoxic activity of novel ethyl 4-[4-(4-substitutedpiperidin-1-yl)]benzyl-phenylpyrrolo[1,2-a]quinoxaline-carboxy late derivatives in myeloid and lymphoid leukemia cell lines
    Eur. J. Med. Chem. 2016, 113, 214-227.
    Impact Factor: 4.519

  33. Ouach, A. ; Pin, F. ; Bertrand, E. ; Vercouillie, J. ; Gulhan, Z. ; Mothes C. ; Deloye, J.-B. ; Guilloteau, D. ; Suzenet, F. ; Chalon, S. ; Routier, S.
    Design of α7 nicotinic acetylcholine receptor ligands using the (Het)Aryl-1,2,3-triazole core: synthesis, in vitro evaluation and SAR studies
    Eur. J. Med. Chem. 2016, 107, 153-164.
    Impact Factor: 4.519

  34. Ouach, A. ; Boulahjar, R. ; Vala, C. ; Bourg, S. ; Bonnet, P. ; Guguen-Guillouzo, C. ; Ravache, M. ; Le Guével, R. ; Lozach, O. ; Lazar, S. ; Troin, Y. ; Meijer, L. ; Ruchaud, S. ; Akssira, M. ; Guillaumet, G. ; Routier, S.
    Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors
    Eur. J. Med. Chem. 2016, 115, 311-325.
    Impact Factor: 4.519

  35. Pânzariu, A.-T. ; Apotrosoasei, M. ; Vasincu, I. M. ; Drăgan, M. ; Constantin, S. ; Buron, F. ; Routier, S. ; Profire, L. ; Tuchilus, C.
    Synthesis and biological evaluation of new 1,3-thiazolidine-4-one derivatives of nitro-l-arginine methyl ester
    Chemistry Central Journal 2016, 10, 6.
    Impact Factor: 2.442

  36. Rodrigues, N. ; Boiaryna, L. ; Vercouillie, J. ; Guilloteau, D. ; Suzenet, F. ; Buron, F. ; Routier, S.
    Tandem silver-catalyzed cyclization/nucleophilic functionalization of 2-alkynylindole-3-carbaldehyde oximes to afford new 2,4-disubstituted γ-carbolines
    Eur. J. Org. Chem. 2016, 5024-5036.
    Impact Factor: 2.834

l'impact factor moyen est de : 3.398



Chapitre de livre - Livre

  1. Buron, F. ; Hiebel, M.-A. ; Mérour, J. Y. ; Plé, K. ; Routier, S.
    Chapter Four - The Chemistry of Sulfur-Containing [5,5]-Fused Ring Systems With a Bridgehead Nitrogen
    Advances in Heterocyclic Chemistry, Scriven, E. F. V.; Ramsden, C. A., Eds. Academic Press 2018, 125, 301-356.

  2. Feizbakhsh, O. ; Place, M. ; Fant, X. ; Buron, F. ; Routier, S. ; Ruchaud, S.
    The mitotic protein kinase haspin and its inhibitors
    Biochemistry, Genetics and Molecular Biology » "Protein Phosphorylation", edited by Claude Prignet 2017, Chap. 2, 31-47.

  3. Serriere, S. ; Doméné, A. ; Vercouillie, J. ; Mothes C. ; Bodard S. ; Rodrigues, N. ; Guilloteau, D. ; Routier, S. ; Page, G. ; Chalon, S.
    Assessment of the protection of dopaminergic neurons by an α7 nicotinic receptor agonist, PHA 543613 using [18F]LBT-999 in a Parkinson’s disease rat model
    eBook, Innovative Radiopharmaceuticals in Oncology and Neurology. Edited by : Françoise Kraeber-Bodéré, Jacques Barbet, Michel Chérel and Denis Guilloteau Published in : Frontiers in Medicine 2017, 8-14.

Articles à comité de lecture (Rang B)

  1. Sava, A. ; Panainte, A. ; Bibire, N. ; Constantin, S. ; Fosca, A. V. ; Buron, F. ; Routier, S. ; Profire, L.
    A rapid, simple and sensitive spectrophotometric method for the determination of no from no donors
    Pharmacy 2020, 124, 678-684.

  2. Constantin, S. ; Vasincu, I. ; Apotrosoasei, M. ; Lupaşcu, F. ; Taușer, G. ; Confederat, L. ; Iacob, A. ; Sava, A. ; Buron, F. ; Routier, S. ; Profire, L.
    Optimization of the synthesis of some new thiazolidine-4-one derivatives with xanthine scaffold
    Rev. Med. Chir. Soc. Med. Nat. Iasi 2017, 121, 438-443.

  3. Iacob, A. ; Drăgan, M. ; Constantin, S. ; Lupaşcu, F. ; Confederat, L. ; Buron, F. ; Routier, S. ; Profire, L.
    Evaluation of antioxidant activity of some imines derivatives of L-arginine
    Rev. Med. Chir. Soc. Med. Nat. Iasi 2016, 120, 439-444.

Acte de colloque

  1. Aci-Sèche, S. ; Buron, F. ; Robin, L. ; Suzenet, F. ; Routier, S.
    30ièmes Journées Franco-Belges de Pharmacochimie
    Pharmaceuticals 2016, 9, 73.