Publications des 5 dernières années

Vous trouverez ici la liste des publications de l'équipe sur les 5 dernières années, pour avoir l'ensemble des données vous pouvez consulter la page des productions.

Articles à comité de lecture (rang A)

  1. Bosc, N. ; Muller, C. ; Hoffer, L. ; Lagorce, D. ; Bourg, S. ; Derviaux, C. ; Gourdel, M.-E. ; Rain, J.-C. ; Miller, T. W. ; Villoutreix, B. O. ; Miteva, M. A. ; Bonnet, P. ; Morelli, X. ; Sperandio, O. ; Roche, P.
    Fr-PPIChem: An academic compound library dedicated to protein–protein interactions
    ACS Chem. Biol. 2020, 15, 1566–1574.
    Impact Factor: 4.374

  2. Bournez, C. ; Carles, F. ; Peyrat, G. ; Aci-Sèche, S. ; Bourg, S. ; Meyer, C. ; Bonnet, P.
    Comparative assessment of protein kinase inhibitors in public databases and in PKIDB
    Molecules 2020, 25, 3226.
    Impact Factor: 3.267

  3. Braka, A. ; Garnier, N. ; Bonnet, P. ; Aci-Sèche, S.
    Residence time prediction of type 1 and 2 kinase inhibitors from unbinding simulations
    J. Chem. Inf. Model. 2020, 60, 342-348.
    Impact Factor: 3.966

  4. Elie, J. ; Feizbakhsh, O. ; Desban, N. ; Josselin, B. ; Baratte, B. ; Bescond, A. ; Duez, J. ; Fant, X. ; Bach, S. ; Marie, D. ; Place, M. ; Ben Salah, S. ; Chartier, A. ; Berteina-Raboin, S. ; Chaikuad, A. ; Knapp, S. ; Carles, F. ; Bonnet, P. ; Buron, F. ; Routier, S. ; Ruchaud, S.
    Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation
    J. Enzym. Inhib. Med. Chem. 2020, 35, 1840–1853.
    Impact Factor: 4.673

  5. Fogha, J. ; Diharce, J. ; Obled, A. ; Aci-Sèche, S. ; Bonnet, P.
    Computational analysis of crystallization additives for the identification of New allosteric sites
    ACS Omega 2020, 5, 2114-2122.
    Impact Factor: 2.584

  6. Ibrahim, N. ; Bonnet, P. ; Brion, J.-D. ; Peyrat, J.-F. ; Brignon, J. ; Levaique, H. ; Josselin, B. ; Robert, T. ; Colas, P. ; Bach, S. ; Messaoudi, S. ; Alami, M. ; Hamze
    Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency
    Eur. J. Med. Chem. 2020, 199, 112355.
    Impact Factor: 4.833

  7. Raimbault, A. ; Ma, C. M. A. ; Ferri, M. ; Bäurer, S. ; Bonnet, P. ; Bourg, S. ; Lämmerhofer, M. ; West, C.
    Cinchona-based zwitterionic stationary phases: Exploring retention and enantioseparation mechanisms in supercritical fluid chromatography with a fragmentation approach
    J. Chromatogr. A 2020, 1612, 460689.
    Impact Factor: 3.858

  8. Diharce, J. ; Cueto, M. ; Beltramo, M. ; Aucagne, V. ; Bonnet, P.
    In silico peptide ligation: iterative residue docking and linking as a new approach to predict protein-peptide interactions
    Molecules 2019, 24, 1351.
    Impact Factor: 3.06

  9. Driowya, M. ; Guillot, R. ; Bonnet, P. ; Guillaumet, G.
    Development of novel and efficient processes for the synthesis of 5-amino and 5-iminoimidazo[1,2-a]imidazoles via three-component reaction catalyzed by zirconium(IV) chloride
    Frontiers in Chemistry 2019, 7, 457-465.
    Impact Factor: 3.782

  10. Duval, J. ; Colas, C. ; Bonnet, P. ; Lesellier, E.
    Hyphenation of ultra-​high performance supercritical fluid chromatography with atmospheric pressure chemical ionisation high resolution mass spectrometry: Part 2. Study of chromatographic and mass spectrometry parameters for the analysis of natural non-​polar compounds
    J. Chromatogr. A 2019, 1596, 199-208.
    Impact Factor: 3.858

  11. Gally, J.-M. ; Bourg, S. ; Fogha, J. ; Do Q.T. ; Aci-Sèche, S. ; Bonnet, P.
    VSPrep: A KNIME workflow for the preparation of molecular databases for virtual screening
    Current Medicinal Chemistry 2019, 26, 1.
    Impact Factor: 3.894

  12. Sirbu, D. ; Diharce, J. ; Martinić, I. ; Chopin, N. ; Eliseeva, S. ; Guillaumet, G. ; Petoud, S. ; Bonnet, P. ; Suzenet, F.
    An original class of small sized molecules as versatile fluorescent probes for cellular imaging
    Chem. Commun. 2019, 54, 7776-7779.
    Impact Factor: 6.164

  13. Carles, F. ; Bourg, S. ; Meyer, C. ; Bonnet, P.
    PKIDB: A curated, annotated and updated database of protein kinase inhibitors in clinical trials
    Molecules 2018, 23, 908.
    Impact Factor: 3.06

  14. Couly, F. ; Harari, M. ; Dubouilh-Benard, C. ; Bailly, L. ; Petit, E. ; Diharce, J. ; Bonnet, P. ; Meijer, L. ; Fruit, C. ; Besson, T.
    Development of kinase inhibitors via metal-catalyzed C–H arylation of 8-alkyl-thiazolo[5,4-f ]-quinazolin-9-ones designed by fragment-growing studies
    Molecules 2018, 23, 2181.
    Impact Factor: 3.06

  15. Driowya, M. ; Allouchi, H. ; Gally, J.-M. ; Bonnet, P. ; Guillaumet, G.
    Synthesis of novel series of 7,7′-(substituted methylene)bis-imidazo[1,2-b]pyrazoles via an acid catalyzed one-pot three-component reaction
    New Journal of Chemistry 2018, 42, 5728-5741.
    Impact Factor: 3.069

  16. Khater, S. ; Canault, B. ; Azzimani, T. ; Bonnet, P. ; West, C.
    Thermodynamic enantioseparation behavior of phenylthiohydantoin-amino acid derivatives in supercritical fluid chromatography on polysaccharide chiral stationary phases
    Journal of Separation Science 2018, 41, 1450-1459.
    Impact Factor: 2.516

  17. Oyallon, B. ; Brachet-Botineau, M. ; Logé, C. ; Bonnet, P. ; Souab, M. ; Robert, T. ; Ruchaud, S. ; Bach, S. ; Berthelot, P. ; Gouilleux, F. ; Viaud-Massuard, M. C. ; Denevault-Sabourin, C.
    Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors
    Eur. J. Med. Chem. 2018, 154, 101-109.
    Impact Factor: 4.833

  18. Soleilhac, E. ; Brillet-Guéguen, L. ; Roussel, V. ; Prudent, R. ; Touquet, B. ; Dass, S. ; Aci-Sèche, S. ; Kasam, V. ; Barette, C. ; Imberty, A. ; Breton, V. ; Vantard, M. ; Horvath, D. ; Botté, C. ; Tardieux, I. ; Roy, S. ; Maréchal, E. ; Lafanechère, L.
    Specific targeting of plant and apicomplexa parasite tubulin through differential screening using in silico and assay-based approaches
    Int. J. Mol. Sci. 2018, 19, 3085.
    Impact Factor: 4.183

  19. Bosc, N. ; Wroblowski, B. ; Meyer, C. ; Bonnet, P.
    Prediction of protein kinase-ligand interactions through 2.5D kinochemometrics
    J. Chem. Inf. Model. 2017, 57, 93-101.
    Impact Factor: 3.804

  20. Bosc, N. ; Meyer, C. ; Bonnet, P.
    The use of novel selectivity metrics in kinase research
    BMC Bioinformatics 2017, 18, 17.
    Impact Factor: 2.448

  21. Canault, B. ; Bourg, S. ; Vayer, P. ; Bonnet, P.
    Comprehensive Network Map of ADME-Tox Databases
    Molecular Informatics 2017, 36, 1700029.
    Impact Factor: 1.955

  22. Gally, J.-M. ; Bourg, S. ; Do Q.T. ; Aci-Sèche, S. ; Bonnet, P.
    VSPrep: A general KNIME workflow for the preparation of molecules for virtual screening
    Molecular Informatics 2017, 36, 1700023.
    Impact Factor: 1.955

  23. West, C. ; Konjaria, M. L. ; Shashviashvili, N. ; Lemasson, E. ; Bonnet, P. ; Kakava, R. ; Volonterio, A. ; Chankvetadze, B.
    Enantioseparation of novel chiral sulfoxides on chlorinated polysaccharide stationary phases in supercritical fluid chromatography
    J. Chromatogr. A 2017, 1499, 174-182.
    Impact Factor: 3.716

  24. Aci-Sèche, S. ; Ziada, S. ; Braka, A. ; Arora, R. ; Bonnet, P.
    Advanced molecular dynamics simulation methods for kinase drug discovery
    Future Med. Chem. 2016, 8, 545-566.
    Impact Factor: 3.744

  25. Albesa-Jove, D. ; Svetlikova, Z. ; Tersa, M. ; Sancho-Vaello, E. ; Carreras-Gonzalez, A. ; Bonnet, P. ; Arrasate, P. ; Eguskiza, A. ; Angala, S. K. ; Cifuente, J. O. ; Kordulakova, J. ; Jackson, M. ; Mikusova, K. ; Guerin, M. E.
    Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA
    Nature Communications 2016, 7, 10906.
    Impact Factor: 11.47

  26. Arora, R. ; Di Michele, M. ; Stes, E. ; Vandermarliere, E. ; Martens, L. ; Gevaert, K. ; Van Heerde, E. ; Linders, J. T. M. ; Brehmer, D. ; Jacoby, E. ; Bonnet, P.
    Correction to structural investigation of B-Raf paradox breaker and inducer inhibitors
    J. Med. Chem. 2016, 59, 6973.
    Impact Factor: 5.589

  27. Chaikuad, A. ; Diharce, J. ; Schroder, M. ; Foucourt, A. ; Leblond, B. ; Casagrande, A. S. ; Desire, L. ; Bonnet, P. ; Knapp, S. ; Besson, T.
    An unusual binding model of the methyl 9-anilinothiazolo[5,4-f] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) confers high selectivity for dual-specificity tyrosine phosphorylation-regulated kinases
    J. Med. Chem. 2016, 59, 10315–10321.
    Impact Factor: 5.589

  28. Jacob, L. ; Sawma, P. ; Garnier, N. ; Meyer, L. A. ; Fritz, J. ; Hussenet, T. ; Spenlé, C. ; Goetz, J. ; Vermot, J. ; Fernandez, A. ; Baumlin, N. ; Aci-Sèche, S. ; Orend, G. ; Roussel, G. ; Crémel, G. ; Genest, M. ; Hubert, P. ; Bagnard, D.
    Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide
    Oncotarget 2016, 7, 57851-57865.
    Impact Factor: 5.008

  29. Ouach, A. ; Boulahjar, R. ; Vala, C. ; Bourg, S. ; Bonnet, P. ; Guguen-Guillouzo, C. ; Ravache, M. ; Le Guével, R. ; Lozach, O. ; Lazar, S. ; Troin, Y. ; Meijer, L. ; Ruchaud, S. ; Akssira, M. ; Guillaumet, G. ; Routier, S.
    Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors
    Eur. J. Med. Chem. 2016, 115, 311-325.
    Impact Factor: 4.519

  30. Arora, R. ; Di Michele, M. ; Stes, E. ; Vandermarliere, E. ; Martens, L. ; Gevaert, K. ; Van Heerde, E. ; Linders, J. T. M. ; Brehmer, D. ; Jacoby, E. ; Bonnet, P.
    Structural investigation of B-raf paradox breaker and inducer inhibitors
    J. Med. Chem. 2015, 58, 1818-1831.
    Impact Factor: 5.48

  31. Bosc, N. ; Wroblowski, B. ; Aci-Sèche, S. ; Meyer, C. ; Bonnet, P.
    A proteometric analysis of human kinome: insight into discriminant conformation-dependent residues
    ACS Chem. Biol. 2015, 10, 2827-2840.
    Impact Factor: 5.331

  32. Boulahjar, R. ; Ouach, A. ; Bourg, S. ; Bonnet, P. ; Lozach, O. ; Meijer, L. ; Guguen-Guillouzo, C. ; Le Guével, R. ; Lazar, S. ; Akssira, M. ; Troin, Y. ; Guillaumet, G. ; Routier, S.
    Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors
    Eur. J. Med. Chem. 2015, 101, 274-287.
    Impact Factor: 3.902

  33. Di Michele, M. ; Stes, E. ; Vandermarliere, E. ; Arora, R. ; Astorga-Wells, J. ; Vandenbussche, J. ; Van Heerde, E. ; Zubarev, R. ; Bonnet, P. ; Linders, J. T. M. ; Jacoby, E. ; Brehmer, D. ; Martens, L. ; Gevaert, K.
    Limited proteolysis combined with stable isotope labeling reveals conformational changes in protein (pseudo)kinases upon binding small molecules
    J Proteome Res 2015, 14, 4179-4193.
    Impact Factor: 4.245

  34. Johnson, C. N. ; Adelinet, C. ; Berdini, V. ; Beke, L. ; Bonnet, P. ; Brehmer, D. ; Calo, F. ; Coyle, J. E. ; Day, P. J. ; Frederickson, M. ; Freyne, E. J. E. ; Gilissen, R. A. H. J. ; Hamlett, C. C. F. ; Howard, S. ; Meerpoel, L. ; Mevellec, L. ; McMenamin, R. ; Pasquier, E. ; Patel, S. ; Rees, D. C. ; Linders, J. T. M.
    Structure-based design of type II inhibitors applied to maternal embryonic leucine zipper kinase
    ACS Med. Chem. Lett. 2015, 6, 31-6.
    Impact Factor: 3.073

  35. Johnson, C. N. ; Berdini, V. ; Beke, L. ; Bonnet, P. ; Brehmer, D. ; Coyle, J. E. ; Day, P. J. ; Frederickson, M. ; Freyne, E. J. E. ; Gilissen, R. A. H. J. ; Hamlett, C. C. F. ; Howard, S. ; Meerpoel, L. ; McMenamin, R. ; Patel, S. ; Rees, D. C. ; Sharff, A. ; Sommen, F. ; Wu, T. ; Linders, J. T. M.
    Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase
    ACS Med. Chem. Lett. 2015, 6, 25-30.
    Impact Factor: 3.073

  36. Rey-Rodriguez, R. ; Retailleau, P. ; Bonnet, P. ; Gillaizeau, I.
    Iron-catalyzed trifluoromethylation of enamide
    Chem. Eur. J. 2015, 21, 3572-3575.
    Impact Factor: 5.771

  37. Sari, O. ; Roy, V. ; Metifiot, M. ; Marchand, C. ; Pommier, Y. ; Bourg, S. ; Bonnet, P. ; Schinazi, R.F. ; Agrofoglio, L. A.
    Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase
    Eur. J. Med. Chem. 2015, 104, 127-138.
    Impact Factor: 3.902

l'impact factor moyen est de : 4.152



Chapitre de livre - Livre

  1. Ziada, S. ; Braka, A. ; Diharce, J. ; Aci-Sèche, S. ; Bonnet, P.
    Enhanced molecular dynamics methods applied to drug design projects
    Methods in Molecular biology 2018, 1762, 403-426.

Acte de colloque

  1. Couly, F. ; Diharce, J. ; Bonnet, P. ; Meijer, L. ; Fruit, C. ; Besson, T.
    Conception of DYRK1A kinase inhibitors via metal-catalyzed C–H arylation, inspired by fragment-growing studies
    Proceedings of the 4th International Electronic Conference on Medicinal Chemistry session ECMC-4 2018, .

  2. Koptelov, M. ; Zimmermann, A. ; Bonnet, P. ; Bureau, R. ; Crémilleux, B.
    PrePeP – A tool for the identification and characterization of pan assay interference compounds
    Proceedings of the 24th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining 2018, 462-471.

  3. Aci-Sèche, S. ; Buron, F. ; Robin, L. ; Suzenet, F. ; Routier, S.
    30ièmes Journées Franco-Belges de Pharmacochimie
    Pharmaceuticals 2016, 9, 73.

Vulgarisation

  1. Aci-Sèche, S. ; Bonnet, P. ; Younès, S.
    Une simulation numérique pour mieux sélectionner les médicaments avant les essais cliniques
    Actualités de l'INC 2020, .

  2. Fogha, J. ; Aci-Sèche, S. ; Maurer, E. ; Laurans, C. ; Ohlmann, P. ; Saillot, C. ; Toumi, H. ; Lespessailles, E. ; Bonnet, P.
    Projet de recherche dans l'arthrose du genou
    Journal "Bouge ton rhumatisme" 2017, Nov., 31.