HRMS Platform FR 2708
General overview:
The HRMS platform (FR 2708) is the result of the Research Federation "Physics and Chemistry of Life" (PCV), created in 2004. It brings together two laboratories in Orléans:
- ICOA: Institute of Organic and Analytical Chemistry, UMR CNRS 7311
- CBM: Center of Molecular Biophysics, UPR CNRS 4301
The platform has two UHR-Q-TOF instruments, one located at the CBM and the other at the ICOA.
At ICOA, the UHR-QTOF instrument is equipped with a CID fragmentation module, mainly used for the structural characterization of small molecules.
This instrument can be coupled with various existing chromatographic systems (UHPLC, nanoUHPLC, SFC and CE) and has a number of different sources: ESI, nanoESI, APCI and APPI, which allows the ionisation of a very wide range of compounds.
The platform also has access to
- a MALDI-TOF
- a pipetting machine for performing colorimetric or enzymatic tests, for pharmacokinetic studies via sample repair by solid phase extraction
- a UV-Visible and fluorescence plate reader
Federation website: https://fr2708.cnrs.fr