Publications des 5 dernières années

Vous trouverez ici la liste des publications de l'équipe sur les 5 dernières années, pour avoir l'ensemble des données vous pouvez consulter la page des productions.

Articles à comité de lecture (rang A)

  1. Carles, F. ; Bourg, S. ; Meyer, C. ; Bonnet, P.
    PKIDB: A curated, annotated and updated database of protein kinase inhibitors in clinical trials
    Molecules 2018, 23, 908.
    Impact Factor: 2.861

  2. Driowya, M. ; Allouchi, H. ; Gally, J.-M. ; Bonnet, P. ; Guillaumet, G.
    Synthesis of novel series of 7,7′-(substituted methylene)bis-imidazo[1,2-b]pyrazoles via an acid catalyzed one-pot three-component reaction
    New Journal of Chemistry 2018, 42, 5728-5741.
    Impact Factor: 3.269

  3. Bosc, N. ; Wroblowski, B. ; Meyer, C. ; Bonnet, P.
    Prediction of protein kinase-ligand interactions through 2.5D kinochemometrics
    J. Chem. Inf. Model. 2017, 57, 93-101.
    Impact Factor: 3.657

  4. Bosc, N. ; Meyer, C. ; Bonnet, P.
    The use of novel selectivity metrics in kinase research
    BMC Bioinformatics 2017, 18, 17.
    Impact Factor: 2.435

  5. Canault, B. ; Bourg, S. ; Vayer, P. ; Bonnet, P.
    Comprehensive Network Map of ADME-Tox Databases
    Molecular Informatics 2017, 36, 1700029.
    Impact Factor: 1.647

  6. Gally, J.-M. ; Bourg, S. ; Do Q.T. ; Aci-Sèche, S. ; Bonnet, P.
    VSPrep: A general KNIME workflow for the preparation of molecules for virtual screening
    Molecular Informatics 2017, 36, 1700023.
    Impact Factor: 1.647

  7. West, C. ; Konjaria, M. L. ; Shashviashvili, N. ; Lemasson, E. ; Bonnet, P. ; Kakava, R. ; Volonterio, A. ; Chankvetadze, B.
    Enantioseparation of novel chiral sulfoxides on chlorinated polysaccharide stationary phases in supercritical fluid chromatography
    J. Chromatogr. A 2017, 1499, 174-182.
    Impact Factor: 3.981

  8. Aci-Sèche, S. ; Ziada, S. ; Braka, A. ; Arora, R. ; Bonnet, P.
    Advanced molecular dynamics simulation methods for kinase drug discovery
    Future Med. Chem. 2016, 8, 545-566.
    Impact Factor: 3.744

  9. Albesa-Jove, D. ; Svetlikova, Z. ; Tersa, M. ; Sancho-Vaello, E. ; Carreras-Gonzalez, A. ; Bonnet, P. ; Arrasate, P. ; Eguskiza, A. ; Angala, S. K. ; Cifuente, J. O. ; Kordulakova, J. ; Jackson, M. ; Mikusova, K. ; Guerin, M. E.
    Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA
    Nature Communications 2016, 7, 10906.
    Impact Factor: 11.47

  10. Arora, R. ; Di Michele, M. ; Stes, E. ; Vandermarliere, E. ; Martens, L. ; Gevaert, K. ; Van Heerde, E. ; Linders, J. T. M. ; Brehmer, D. ; Jacoby, E. ; Bonnet, P.
    Correction to structural investigation of B-Raf paradox breaker and inducer inhibitors
    J. Med. Chem. 2016, 59, 6973.
    Impact Factor: 5.589

  11. Chaikuad, A. ; Diharce, J. ; Schroder, M. ; Foucourt, A. ; Leblond, B. ; Casagrande, A. S. ; Desire, L. ; Bonnet, P. ; Knapp, S. ; Besson, T.
    An unusual binding model of the methyl 9-anilinothiazolo[5,4-f] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) confers high selectivity for dual-specificity tyrosine phosphorylation-regulated kinases
    J. Med. Chem. 2016, 59, 10315–10321.
    Impact Factor: 5.589

  12. Jacob, L. ; Sawma, P. ; Garnier, N. ; Meyer, L. A. ; Fritz, J. ; Hussenet, T. ; Spenlé, C. ; Goetz, J. ; Vermot, J. ; Fernandez, A. ; Baumlin, N. ; Aci-Sèche, S. ; Orend, G. ; Roussel, G. ; Crémel, G. ; Genest, M. ; Hubert, P. ; Bagnard, D.
    Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide
    Oncotarget 2016, 7, 57851-57865.
    Impact Factor: 5.008

  13. Ouach, A. ; Boulahjar, R. ; Vala, C. ; Bourg, S. ; Bonnet, P. ; Guguen-Guillouzo, C. ; Ravache, M. ; Le Guével, R. ; Lozach, O. ; Lazar, S. ; Troin, Y. ; Meijer, L. ; Ruchaud, S. ; Akssira, M. ; Guillaumet, G. ; Routier, S.
    Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors
    Eur. J. Med. Chem. 2016, 115, 311-325.
    Impact Factor: 3.447

  14. Arora, R. ; Di Michele, M. ; Stes, E. ; Vandermarliere, E. ; Martens, L. ; Gevaert, K. ; Van Heerde, E. ; Linders, J. T. M. ; Brehmer, D. ; Jacoby, E. ; Bonnet, P.
    Structural investigation of B-raf paradox breaker and inducer inhibitors
    J. Med. Chem. 2015, 58, 1818-1831.
    Impact Factor: 5.48

  15. Bosc, N. ; Wroblowski, B. ; Aci-Sèche, S. ; Meyer, C. ; Bonnet, P.
    A proteometric analysis of human kinome: insight into discriminant conformation-dependent residues
    ACS Chem. Biol. 2015, 10, 2827-2840.
    Impact Factor: 5.331

  16. Boulahjar, R. ; Ouach, A. ; Bourg, S. ; Bonnet, P. ; Lozach, O. ; Meijer, L. ; Guguen-Guillouzo, C. ; Le Guével, R. ; Lazar, S. ; Akssira, M. ; Troin, Y. ; Guillaumet, G. ; Routier, S.
    Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors
    Eur. J. Med. Chem. 2015, 101, 274-287.
    Impact Factor: 3.447

  17. Di Michele, M. ; Stes, E. ; Vandermarliere, E. ; Arora, R. ; Astorga-Wells, J. ; Vandenbussche, J. ; Van Heerde, E. ; Zubarev, R. ; Bonnet, P. ; Linders, J. T. M. ; Jacoby, E. ; Brehmer, D. ; Martens, L. ; Gevaert, K.
    Limited proteolysis combined with stable isotope labeling reveals conformational changes in protein (pseudo)kinases upon binding small molecules
    J Proteome Res 2015, 14, 4179-4193.
    Impact Factor: 4.245

  18. Johnson, C. N. ; Berdini, V. ; Beke, L. ; Bonnet, P. ; Brehmer, D. ; Coyle, J. E. ; Day, P. J. ; Frederickson, M. ; Freyne, E. J. E. ; Gilissen, R. A. H. J. ; Hamlett, C. C. F. ; Howard, S. ; Meerpoel, L. ; McMenamin, R. ; Patel, S. ; Rees, D. C. ; Sharff, A. ; Sommen, F. ; Wu, T. ; Linders, J. T. M.
    Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase
    ACS Med. Chem. Lett. 2015, 6, 25-30.
    Impact Factor: 3.073

  19. Johnson, C. N. ; Adelinet, C. ; Berdini, V. ; Beke, L. ; Bonnet, P. ; Brehmer, D. ; Calo, F. ; Coyle, J. E. ; Day, P. J. ; Frederickson, M. ; Freyne, E. J. E. ; Gilissen, R. A. H. J. ; Hamlett, C. C. F. ; Howard, S. ; Meerpoel, L. ; Mevellec, L. ; McMenamin, R. ; Pasquier, E. ; Patel, S. ; Rees, D. C. ; Linders, J. T. M.
    Structure-based design of type II inhibitors applied to maternal embryonic leucine zipper kinase
    ACS Med. Chem. Lett. 2015, 6, 31-6.
    Impact Factor: 3.073

  20. Rey-Rodriguez, R. ; Retailleau, P. ; Bonnet, P. ; Gillaizeau, I.
    Iron-catalyzed trifluoromethylation of enamide
    Chem. Eur. J. 2015, 21, 3572-3575.
    Impact Factor: 5.696

  21. Sari, O. ; Roy, V. ; Metifiot, M. ; Marchand, C. ; Pommier, Y. ; Bourg, S. ; Bonnet, P. ; Schinazi, R.F. ; Agrofoglio, L. A.
    Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase
    Eur. J. Med. Chem. 2015, 104, 127-138.
    Impact Factor: 3.447

  22. West, C. ; Lemasson, E. ; Khater, S. ; Lesellier, E.
    An attempt to estimate ionic interactions with phenyl and pentafluorophenyl stationary phases in supercritical fluid chromatography
    J. Chromatogr. A 2015, 1412, 126-138.
    Impact Factor: 4.169

  23. West, C. ; Khalikova, M. A. ; Lesellier, E. ; Héberger, K.
    Sum of ranking differences to rank stationary phases used in packed column supercritical fluid chromatography
    J. Chromatogr. A 2015, 1409, 241-250.
    Impact Factor: 4.169

  24. Aci-Sèche, S. ; Sawma, P. ; Hubert, P. ; Sturgis, J. N. ; Bagnard, D. ; Jacob, L. ; Genest, M. ; Garnier, N.
    Transmembrane recognition of the semaphorin Co-receptors neuropilin 1 and plexin A1: coarse-grained simulations
    PLoS ONE 2014, 9, e97779.
    Impact Factor: 3.234

  25. Arpel, A. ; Sawma, P. ; Spenlé, C. ; Fritz, J. ; Meyer, L. ; Garnier, N. ; Velàzquez-Quesada, I. ; Hussenet, T. ; Aci-Sèche, S. ; Baumlin, N. ; Genest, M. ; Brasse, D. ; Hubert, P. ; Crémel, G. ; Orend, G. ; Laquerrière, P. ; Bagnard, D.
    Transmembrane domain targeting peptide antagonizing ErbB2/Neu inhibits breast tumor growth and metastasis
    Cell Reports 2014, 8, 1-8.
    Impact Factor: 8.358

  26. Atzori, A. ; Bruce, N.J. ; Burusco, K.K. ; Wroblowski, B. ; Bonnet, P. ; Bryce, R. A.
    Exploring protein kinase conformation using swarm-enhanced sampling molecular dynamics
    J. Chem. Inf. Model. 2014, 54, 2764-2775.
    Impact Factor: 3.738

  27. Cheray, M. ; Nadaradjane, A. ; Bonnet, P. ; Routier, S. ; Valette, F. M. ; Cartron, P. F.
    Specific inhibition of DNMT1/CFP1 reduces cancer phenotypes and enhances chemotherapy effectiveness
    Epigenomics 2014, 3, 267-275.
    Impact Factor: 5.215

  28. Dehbi, O. ; Tikad, A. ; Bourg, S. ; Bonnet, P. ; Lozach, O. ; Meijer, L. ; Aadil, M. ; Akssira, M. ; Guillaumet, G. ; Routier, S.
    Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors
    Eur. J. Med. Chem. 2014, 80, 352-363.
    Impact Factor: 3.432

  29. Khater, S. ; Zhang, Y. ; West, C.
    Insights into chiral recognition mechanism in supercritical fluid chromatography III. Non-halogenated polysaccharide stationary phases
    J. Chromatogr. A 2014, 1363, 278-293.
    Impact Factor: 4.258

  30. Khater, S. ; West, C.
    Insights into chiral recognition mechanisms in supercritical fluid chromatography V. Effect of the nature and proportion of alcohol mobile phase modifier with amylose and cellulose tris-(3,5-dimethylphenylcarbamate) stationary phases
    J. Chromatogr. A 2014, 1373, 197-210.
    Impact Factor: 4.258

  31. Khater, S. ; Zhang, Y. ; West, C.
    Insights into chiral recognition mechanism in supercritical fluid chromatography IV. Chlorinated polysaccharide stationary phases
    J. Chromatogr. A 2014, 1363, 294-310.
    Impact Factor: 4.258

  32. Mérour, J. Y. ; Buron, F. ; Plé, K. ; Bonnet, P. ; Routier, S.
    The azaindole framework in the design of kinase inhibitors
    Molecules 2014, 19, 19935-19979.
    Impact Factor: 2.416

  33. Saurat, T. ; Buron, F. ; Rodrigues, N. ; De Tauzia, M. L. ; Colliandre, L. ; Bourg, S. ; Bonnet, P. ; Guillaumet, G. ; Akssira, M. ; Corlu, A. ; Guillouzo, C. ; Berthier, P. ; Rio, P. ; Jourdan, M.-L. ; Bénédetti, H. ; Routier, S.
    Design, synthesis, and biological activity of pyridopyrimidine scaffolds as novel PI3K/mTOR dual inhibitors
    J. Med. Chem. 2014, 57, 613-631.
    Impact Factor: 5.48

  34. Atzori, A. ; Baker, A. E. ; Chiu, M. ; Bryce, R. A. ; Bonnet, P.
    Effect of sequence and stereochemistry reversal on p53 peptide mimicry
    PLoS ONE 2013, 8, e68723.
    Impact Factor: 3.534

  35. Dubernet, M. ; Duguet, N. ; Colliandre, L. ; Berini, C. ; Helleboid, S. ; Bourotte, M. ; Daillet, M. ; Maingot, L. ; Daix, S. ; Delhomel, J.-F. ; Morin-Allory, L. ; Routier, S. ; Walczak, R.
    Identification of new nonsteroidal RORα ligands; Related structure–activity relationships and docking studies
    ACS Med. Chem. Lett. 2013, 4, 504-508.
    Impact Factor: 3.073

  36. Khater, S. ; Zhang, Y. ; West, C.
    In-depth characterization of six cellulose tris-(3,5-dimethylphenylcarbamate) chiral stationary phases in supercritical fluid chromatography
    J. Chromatogr. A 2013, 1303, 83-93.
    Impact Factor: 4.258

  37. Martinez-Sanz, J. ; Bonnet, P. ; Lozano, S. ; Arrault, Al. ; Morin-Allory, L. ; Vayer, P.
    New QSAR models for human cytochromes P450, 1A2, 2D6 and 3A4 implicated in the metabolism of drugs. relevance of dataset on model development
    Molecular Informatics 2013, 32, 573-577.
    Impact Factor: 2.013

  38. Mathis, G. ; Bourg, S. ; Aci-Sèche, S. ; Truffert, J.-C. ; Asseline, U.
    Synthesis and Properties of 2’-O-neopentyl modified oligonucleotides
    Org. Biomol. Chem. 2013, 11, 1345-1357.
    Impact Factor: 3.562

  39. West, C. ; Lesellier, E.
    Chemometric methods to classify stationary phases for achiral supercritical fluid chromatography
    J. Chemometrics 2012, 26, 52-65.
    Impact Factor: 1.937

l'impact factor moyen est de : 4.090



Chapitre de livre - Livre

  1. Ziada, S. ; Braka, A. ; Diharce, J. ; Aci-Sèche, S. ; Bonnet, P.
    Enhanced molecular dynamics methods applied to drug design projects
    Methods in Molecular biology 2018, 1762, 403-426.

Articles à comité de lecture (rang B)

  1. West, C.
    Statistics for analysts who hate statistics, part I: Collect and examine your data
    LC-GC North America 2016, 34, 420-421.

  2. West, C.
    Statistics for analysts who hate statistics, part III: Principal component analysis
    LC-GC North America 2016, 34, .

  3. West, C.
    Statistics for analysts who hate statistics, part II: Linear regression and Quantitative structure-retention relationships
    LC-GC North America 2016, 34, 742-745.

  4. Rognan, D. ; Bonnet, P.
    Les chimiothèques et le criblage virtuel
    Med. Sci. 2014, 30, 1152-1160.

Acte de colloque

  1. Aci-Sèche, S. ; Buron, F. ; Robin, L. ; Suzenet, F. ; Routier, S.
    30ièmes Journées Franco-Belges de Pharmacochimie
    Pharmaceuticals 2016, 9, 73.

Vulgarisation

  1. Fogha, J. ; Aci-Sèche, S. ; Maurer, E. ; Laurans, C. ; Ohlmann, P. ; Saillot, C. ; Toumi, H. ; Lespessailles, E. ; Bonnet, P.
    Projet de recherche dans l'arthrose du genou
    Journal "Bouge ton rhumatisme" 2017, Nov., 31.

  2. Bonnet, P.
    L’informatique moléculaire,dans la course aux nouveaux candidats médicaments
    Microscoop, le magazine de la délégation CNRS Centre Limousin Poitou-Charentes 2013, HS2013, 28-29.